Internal Medicine Morning Report

Griesdale DE, de Souza RJ, van Dam RM, Heyland DK, Cook DJ, Malhotra A, Dhaliwal R, Henderson WR, Chittock DR, Finfer S, Talmor D. Intensive insulin therapy and mortality among critically ill patients: a meta-analysis including NICE-SUGAR study data. CMAJ. 2009 Apr 14;180(8):821-7. Epub 2009 Mar 24. [Abstract] PMID 19318387

Medical Subject Headings

• *Cause of Death
• Critical Illness/*mortality/therapy
• Hypoglycemia/*chemically induced/*mortality
• Insulin/administration & dosage/*adverse effects

Van den Berghe G, Wilmer A, Hermans G, Meersseman W, Wouters PJ, Milants I, Van Wijngaerden E, Bobbaers H, Bouillon R. Intensive insulin therapy in the medical ICU. N Engl J Med. 2006 Feb 2;354(5):449-61. [Abstract] PMID 16452557

Medical Subject Headings

• Critical Illness/classification/mortality/*therapy
• Hypoglycemic Agents/*administration & dosage
• Insulin/*administration & dosage
• *Intensive Care

Finfer S, Chittock DR, Su SY, Blair D, Foster D, Dhingra V, Bellomo R, Cook D, Dodek P, Henderson WR, Hebert PC, Heritier S, Heyland DK, McArthur C, McDonald E, Mitchell I, Myburgh JA, Norton R, Potter J, Robinson BG, Ronco JJ. Intensive versus conventional glucose control in critically ill patients. N Engl J Med. 2009 Mar 26;360(13):1283-97. Epub 2009 Mar 24. [Abstract] PMID 19318384

Medical Subject Headings

• *Blood Glucose/analysis
• Critical Illness/mortality/*therapy
• Hyperglycemia/*drug therapy
• Hypoglycemic Agents/adverse effects/*therapeutic use
• Insulin/adverse effects/*therapeutic use
• Intensive Care/*methods

Dr. Jadoon, Internal Medicine Resident
Lib: DD

Benjamin M, Terrell DR, Vesely SK, Voskuhl GW, Dezube BJ, Kremer Hovinga JA, Lammle B, George JN. Frequency and significance of HIV infection among patients diagnosed with thrombotic thrombocytopenic purpura. Clin Infect Dis. 2009 Apr 15;48(8):1129-37. [Abstract] PMID 19275493

Medical Subject Headings

• HIV Infections/*complications/*epidemiology/pathology

Brecher ME, Hay SN, Park YA. Is it HIV TTP or HIV-associated thrombotic microangiopathy? J Clin Apher. 2008;23(6):186-90. [Abstract] PMID 18973113

Medical Subject Headings

• HIV Infections/*complications
• Purpura, Thrombotic Thrombocytopenic/etiology/*pathology/therapy

Dr. Kanikireddy, Internal Medicine Resident
Lib: DD

Klein PA, Clark RA. An evidence-based review of the efficacy of antihistamines in relieving pruritus in atopic dermatitis. Arch Dermatol. 1999 Dec;135(12):1522-5. [Abstract] PMID 10606058

Medical Subject Headings

• Dermatitis, Atopic/*drug therapy/etiology
• *Evidence-Based Medicine
• Histamine H1 Antagonists/*administration & dosage/adverse effects
• Pruritus/*drug therapy/etiology

O'Donoghue M, Tharp MD. Antihistamines and their role as antipruritics. Dermatol Ther. 2005 Jul-Aug;18(4):333-40. [Abstract] PMID 16297006

Medical Subject Headings

• Antipruritics/pharmacokinetics/*pharmacology
• Histamine H1 Antagonists/pharmacokinetics/*pharmacology
• Pruritus/*drug therapy

Mukesh Sharma, MD, Internal Medicine Resident
Lib: DW

Glantz MJ, Jaeckle KA, Chamberlain MC, Phuphanich S, Recht L, Swinnen LJ, Maria B, LaFollette S, Schumann GB, Cole BF, Howell SB. A randomized controlled trial comparing intrathecal sustained-release cytarabine (DepoCyt) to intrathecal methotrexate in patients with neoplastic meningitis from solid tumors. Clin Cancer Res. 1999 Nov;5(11):3394-402. [Abstract] PMID 10589750

Medical Subject Headings

• Antimetabolites, Antineoplastic/administration & dosage/*therapeutic use
• Cytarabine/administration & dosage/*therapeutic use
• Meningeal Neoplasms/*drug therapy/mortality/*secondary
• Methotrexate/administration & dosage/*therapeutic use

Glantz MJ, Cole BF, Recht L, Akerley W, Mills P, Saris S, Hochberg F, Calabresi P, Egorin MJ. High-dose intravenous methotrexate for patients with nonleukemic leptomeningeal cancer: is intrathecal chemotherapy necessary? J Clin Oncol. 1998 Apr;16(4):1561-7. [Abstract] PMID 9552066

Medical Subject Headings

• Antimetabolites, Antineoplastic/*administration & dosage/adverse
• Arachnoid Cysts/*drug therapy
• Methotrexate/*administration & dosage/adverse effects/analysis/*pharmacokinetics
• Neoplasms/*drug therapy/mortality

Kim DY, Lee KW, Yun T, Park SR, Jung JY, Kim DW, Kim TY, Heo DS, Bang YJ, Kim NK. Comparison of intrathecal chemotherapy for leptomeningeal carcinomatosis of a solid tumor: methotrexate alone versus methotrexate in combination with cytosine arabinoside and hydrocortisone. Jpn J Clin Oncol. 2003 Dec;33(12):608-12. [Abstract] PMID 14769837

Medical Subject Headings

• Adenocarcinoma/*drug therapy/mortality/pathology
• Antineoplastic Combined Chemotherapy Protocols/*therapeutic use
• Meningeal Neoplasms/*drug therapy/mortality/pathology
• Methotrexate/*administration & dosage

Kamran Shahid, MD, Medicine/Pediatrics
Lib: KAC

Gardner WN. The pathophysiology of hyperventilation disorders. Chest. 1996 Feb;109(2):516-34. [Abstract] PMID 8620731

Medical Subject Headings

• Hyperventilation/diagnosis/etiology/*physiopathology/therapy

BONUS
Mason: Murray & Nadel's Textbook of Respiratory Medicine, 4th ed.
Schematic diagram showing the mechanisms involved in alveolar hyperventilation.

Saritha Boyapati, MD, Internal Medicine Resident
Lib: JC