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| Morphine | 30 mg q3-4h (around the clock dosing) | 30 mg q3-4h | 0.3 mg/kg q3-4h |
| Codeine | 130 mg q3-4h | 60 mg q3-4h | 1 mg/kg q3-4h |
| Hydrocodone | 30 mg q3-4h | 10 mg q3-4h | 0.2 mg/kg q3-4h |
| Oxycodone | 30 mg q3-4h | 10 mg q3-4h | 0.2 mg/kg q3-4h |
Caution: Recommended doses do not apply to patients with
renal or hepatic insufficiency or other conditions affecting drug metabolism
and kinetics. Doses listed for patients with body weight less than 50 kg
cannot be used as initial starting doses in babies less than 6 months of
age. Codeine doses above 65 mg often are not appropriate due to diminishing
incremental analgesia with increasing doses but continually increasing
constipation and other side effects. Doses of aspirin and acetaminophen
in combination opioid/NSAID preparations must also be adjusted to the patient’s
weight.
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