Drugs for Prophylaxis and Treatment of Travelers' Diarrhea in Adults -2000

 


Drug Dosage Comment
Prophylaxis    
Bismuth subsalicylate

(Pepto Bismol)

2 tablets or 2 oz of liquid 4 times a day while traveling May reduce risk by one half. Avoid in persons with contraindications to aspirin. Stools may be blackened.
Treatment Regimens    
Ciprofloxacin (Cipro) 500 mg orally 2 times daily for 1 to 3 days Ofloxacin has less sun sensitivity than ciprofloxacin and a broader spectrum of coverage. Severe dysentery may require longer treatment. Contraindictated in persons < 18 years of age
Ofloxacin (Floxin) 400 mg orally 2 times daily for 1 to 3 days  
Single-dose ofloxacin plus loperamide (Imodium) 400 mg of ofloxacin and 2 tablets of loperamide  

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