Drugs of Choice According to Seizure Type-2000

 


Seizure category Drugs of choice Alternative drugs
Generalized seizures    
Primary generalized, tonic-clonic Valproic acid (Depakene) Carbamazepine (Tegretol), phenytoin (Dilan

tin), primidone (Mysoline), phenobarbital

Primary generalized, absence Ethosuximide (Zarontin), valproic acid Clonazepam (Klonopin)
Primary myoclonic Valproic acid, clonazepam Phenytoin, phenobarbital
Partial seizures    
Partial simple and complex, and secondarily generalized epilepsy Carbamazepine, phenytoin Valproic acid, phenobarbital, primidone
Mixed forms Valproic acid, clonazepam Carbamazepine, phenytoin, phenobarbital
New Drugs    
Partial onset and secondarily generalized   Felbamate (Felbatol), gabapentin (Neurontin), lamotrigine (Lamictal), topiramate (Topamax), tiagabine (Gabatril)

 


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